Cellular therapy of cancer : development of gene therapy based approaches / editor, Robert E. Hawkins.

Includes bibliographical references.

Ch. 1. Challenges of T-cell therapy / Naomi Taylor, Anna Mondino and Balbino Alarcon -- ch. 2. Gene transfer into T cells / David Gilham and Hinrich Abken -- ch. 3. TCR-engineered T cells / Reno Debets and Ton Schumacher -- ch. 4. T-bodies: Antibody-based engineered T-cell receptors / John Bridgeman [and others] -- ch. 5. T-cell engineering and expansion -- GMP issues / Cor Lamers and Ryan Guest -- ch. 6. Clinical trial design / Robert Hawkins, John Haanen and Fiona Thistlethwaite.

Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field.

Print version record.

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