TY - GEN AU - Ptito,Maurice AU - Bouskila,Joseph AU - Ptito,Maurice AU - Bouskila,Joseph TI - The Retina in Health and Disease SN - books978-3-0365-2652-2 PY - 2021/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - Neurosciences KW - eye KW - retina KW - development KW - vascularization KW - hypoxia KW - autophagy KW - programmed cell death KW - cellular senescence KW - retinogenesis KW - altricial bird species KW - precocial bird species KW - senescence-associated galactosidase activity KW - diabetes mellitus KW - retinopathy KW - microvascular KW - complication KW - optical coherence tomography KW - angiography KW - black KW - African-American KW - systemic disease KW - biomarker KW - retinal degenerative diseases KW - mesenchymal stem cells KW - stem cell therapy KW - experimental models KW - clinical trials KW - AMD KW - age-related macular degeneration KW - trichostatin A (TSA) KW - HDAC KW - histone deacetylase KW - vascular endothelial growth factor (VEGF) KW - retinal degeneration KW - endoplasmic reticulum KW - stress response KW - unfolded protein response KW - GRP78 KW - retinal glial cell KW - diabetic retinopathy KW - zebrafish KW - neurovascular unit KW - microvascular complications and dysfunction KW - metabolism KW - motor protein KW - myosin 1C KW - photoreceptor KW - rhodopsin KW - outer segments KW - visual function KW - macroglia KW - astrocytes KW - Müller cells KW - optic nerve crush KW - retinal ganglion cells KW - spinal cord injury KW - signal transducer and activator of transcription 3 KW - epidermal growth factor KW - Drp1 KW - apoptosis KW - mitochondria KW - microglia KW - neurodegeneration KW - multiple sclerosis KW - retinal microglia KW - microglia morphotype KW - light damage KW - functional analysis KW - early detection KW - remodeling KW - lactate KW - GPR81 KW - HCAR1 KW - growth cone KW - dLGN KW - axon KW - 3,5-DHBA KW - kallikrein-kinin system KW - kinin receptors KW - GFAP KW - osteopontin KW - retinal detachment KW - diabetes KW - antioxidants KW - bioenergetics KW - respiration KW - ATP KW - glucagon-like peptide-1 KW - exendin-4 KW - catalase KW - immunohistochemistry KW - electron microscopy KW - Charles Bonnet syndrome KW - EEG KW - visual hallucination KW - resting state KW - high-fat diet KW - gut microbiome KW - gut-retina axis KW - RNA sequencing KW - germ-free mice KW - complement cascade KW - angiogenesis KW - retinal inflammation KW - AII amacrine cell KW - Prox1 KW - parvalbumin KW - gap junction KW - eccentricity KW - ON/OFF asymmetry KW - arterioles KW - betulinic acid KW - ischemia-reperfusion injury KW - reactive oxygen species KW - retinal vessels KW - retinal fluorescence imaging KW - amyloid KW - cognitive decline KW - Alzheimer's disease KW - optic neuritis KW - oxidative stress KW - neuroprotection KW - fingolimod KW - iPSC-RPE KW - retinal pigment epithelium KW - immunodeficient RCS rat KW - ultrathin parylene KW - retinal transplantation KW - CD4+CD25+ KW - inflammation KW - iPSC KW - typical cannabinoid receptors KW - atypical cannabinoid receptors KW - electroretinography KW - monkeys KW - visual system KW - eye inflammation KW - lipopolysaccharide KW - natural bioactive extracts KW - Ac2-26 KW - FPR receptor KW - inflammatory mediators KW - retinal light injury KW - LED screen KW - optical filter KW - retinal protection KW - regeneration KW - progenitor cell KW - hyperglycemia KW - photoreceptors KW - neurod KW - Notch KW - n/a N1 - Open Access N2 - Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy UR - https://mdpi.com/books/pdfview/book/4745 UR - https://directory.doabooks.org/handle/20.500.12854/77126 ER -