TY - BOOK AU - Rodriguez-Rodriguez,Lorna AU - Ganasen,Shridar AU - Hirshfield,Kim M. AU - Khiabanian,Hossein AU - Riedlinger,Gregory TI - Precision medicine oncology: a primer SN - 0813575893 AV - RC261 .P74 2019 U1 - 616.99/4 23 PY - 2019///] CY - New Brunswick PB - Rutgers University Press KW - Cancer KW - Treatment KW - Genetics KW - Technique KW - Neoplasms KW - therapy KW - Precision Medicine KW - methods KW - Medical Oncology KW - Genetic Techniques KW - Clinical Trials as Topic KW - Traitement KW - Génétique KW - MEDICAL KW - General KW - bisacsh KW - fast KW - Electronic books N1 - Includes bibliographical references and index; Preface; Rodriguez-Rodriguez, Lorna / Hirshfield, Kim M. / Ganesan, Shridar --; 1. Genomic Technology/ Next-Generation Sequencing; Khiabanian, Hossein / Ganesan, Shridar / Hirshfield, Kim M. / Riedlinger, Gregory --; 2. The Precision Medicine Oncology Molecular Tumor Board; Ganesan, Shridar / Hirshfield, Kim M. / Riedlinger, Gregory / Rodriguez-Rodriguez, Lorna --; 3. Clinical Research in Precision Medicine Oncology; Hirshfield, Kim M. / Ganesan, Shridar --; 4. Infrastructures in Precision Medicine Oncology; Ganesan, Shridar / Hirshfield, Kim M. --; 5. Future Directions in Precision Medicine Oncology; Ganesan, Shridar / Hirshfield, Kim M. / Rodriguez-Rodriguez, Lorna N2 - Precision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. This is made possible, in part, by the ready availability and reasonable costs of comprehensive DNA and RNA sequencing assays. However, precision medicine is complex and incorporates entirely new types of data and treatment paradigms that are outside of the training of most oncologists in practice today. Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, intended for clinicians, particularly those working in oncology. It provides an accessible introduction to the technological advances in DNA and RNA sequencing, gives a detailed overview of approaches to the interpretation of molecular test results and their point-of-care implementation for individual patients, and describes innovative clinical trial designs in oncology as well as characteristics of the computational infrastructures through which massive quantities of data are collected, stored, and used in precision medicine oncology UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2275711 ER -