TY - BOOK AU - Kavic,Stephen M. TI - Surgery for Crohn's disease T2 - Digestive diseases--research and clinical developments SN - 9781634826914 AV - RC862.E52 U1 - 616.3/44 23 PY - 2015/// CY - New York PB - Nova Biomedical KW - Crohn's disease KW - Surgery KW - Maladie de Crohn KW - Chirurgie KW - HEALTH & FITNESS / Diseases / General KW - bisacsh KW - MEDICAL / Clinical Medicine KW - MEDICAL / Diseases KW - MEDICAL / Evidence-Based Medicine KW - MEDICAL / Internal Medicine KW - Electronic books N1 - Includes bibliographical references and index; Chapter 1: Overview: History, Epidemiology, and Etiology; Abstract; History; Epidemiology; Etiology; Genetic Factors; Environmental Factors; Immune Response and Inflammation; Summary; References; Chapter 2: Diagnosis of Crohn's Disease; Abstract; Presentation and Symptoms; Laboratory Evaluation; Traditional Laboratories; Stool Analysis; Serologic Testing; Genetic Testing; Endoscopic Evaluation; Conclusion; References; Chapter 3: Medical ManagementAbstract; I. Introduction and Goals of Medical Therapy in Crohn's Disease; II. Endpoints of Medical Therapy; III. Pharmacologic Agents Used for Crohn's Disease; III.A. Antibiotics; Mechanism of Action; Efficacy; III.B. 5-Aminosalicylates; Mechanism of Action; Efficacy; Side Effects and Dosing; III.C. Budesonide and Systemic Steroids; Budesonide; Mechanism of Action; Efficacy; Systemic Steroids; Mechanism of Action; Efficacy; Side Effects and Dosing; III.D. Immune Suppressants; Azathioprine and 6-mercaptopurine; Mechanism of Action; Efficacy; Side Effects and DosingMethotrexate; Mechanism of Action; Efficacy; Side Effects and Dosing; III.E. Anti-TNF Therapy; Infliximab; Efficacy; Adalimumab; Efficacy; Certolizumab Pegol; Efficacy; Side Effects and Dosing; III.F. Anti-integrin Agents; Side Effects and Dosing; IV. Combination Therapy; V. Step-Up vs. Top-Down Therapy; VI. De-escalation of Therapy; VII. Therapeutic Drug Monitoring; VIII. Endoscopic Therapy; Conclusion; References; Chapter 4: The Role of Nutrition and Short Gut Syndrome; 1Assistant Professor of Pediatrics,; University of Maryland School of Medicine, US; 2Assistant Professor of Medicine,University of Maryland School of Medicine, US; Abstract; I. Nutrition in IBD; Introduction; Role of Diet; Nutritional Deficiencies; Food Intolerance; Nutritional Markers in IBD; Conclusion -- Nutrition; II. Short Gut Syndrome; Introduction; Pathophysiology; Phases of Adaptation; Acute Phase; Adaptation Phase; Maintenance Phase; Prognosis; Complications; Management of Short Gut Syndrome; TPN; Enteral Nutrition; Medications; Conclusion; References; Chapter 5: Minimally Invasive Surgical Techniques and Outcomes; Abstract; Introduction; Indications and ContraindicationsIleocolic Disease; Complex Disease; Colonic Disease; Preoperative Planning; OR Setup and Positioning; Abdominal Access; Laparoscopic-assisted Ileocecectomy / Right Hemicolectomy; Dissection; Extracorporeal Anastomosis; Alternative Methods of Anastomoses; Laparoscopic Total / Subtotal Colectomy; Mobilization of the Splenic Flexure, Left Colon, and Sigmoid; Surgical Technique in Complex Disease; Fistulas; Single-Site Surgery and New Technologies; Summary; References; Chapter 6: Foregut Surgery; 1Resident in Surgery; University of Maryland Medical Center, US N2 - Crohn's disease is a chronic illness that afflicts millions of patients worldwide. Despite its increasing recognition as a medical specialty within gastroenterology, there has been little attention devoted to Crohn's from a surgical perspective. This volume fills that void and acts as the first catalogue to address the surgical management of Crohn's disease. The goal of this work was to provide surgeons with the latest medical and surgical information to manage patients with Crohn's disease effectively. In this book, contributions from both gastroenterologists describe the history, diagnosis UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1023371 ER -