MARC details
| 000 -LEADER |
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| fixed length control field |
06017naaaa2201393uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/69087 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714194715.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
books978-3-03943-009-3 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039430086 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039430093 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.3390/books978-3-03943-009-3 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
GP |
| Source |
bicssc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nakagawa-Goto, Kyoko |
| Relator code |
edt |
| 9 (RLIN) |
1622670 |
| 245 10 - TITLE STATEMENT |
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| Title |
Antitumor and Anti-HIV Agents from Natural Products |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Basel, Switzerland |
| Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 electronic resource (338 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
|---|
| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
Cancer is the second leading cause of death worldwide, and was accountable for an estimated 9.6 million deaths in 2018. Nowadays, about 1 in 6 deaths in the world is due to cancer. Another major global public health issue is HIV. Over 70 million people have been infected with the HIV virus and about 35 million people have died of HIV-related illness, since the start of the epidemic. We have been fighting against these two serious diseases by finding successful treatments. The discovery of effective drugs is important for fighting cancer and HIV. Natural products, which are secondary metabolites produced by various living organisms, have been playing a principal role in drug discovery and developments, because of their structural and biological diversity. Many clinically used drugs have come from natural products; for example, more than 60% of anticancer drugs currently in clinical use are derived from natural sources. This Special Issue aims to collect original research and review articles focusing on notable and recent contributions to the discovery and development of novel anticancer and anti-HIV drug candidates from natural sources. Up-to-date knowledge from various research fields is welcome. This could be of great interest for scientists working in different research areas, such as natural product chemistry, including isolation and structural elucidation; phytochemistry; medicinal chemistry, including chemically modified natural compounds with improved biological activity; pharmacology; molecular biology; mechanisms of action study using natural products or related compounds; pharmacognosy, etc. Biological studies of natural extracts without an appropriate chemical characterization may not be considered. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
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| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Research & information: general |
| Source of heading or term |
bicssc |
| 9 (RLIN) |
928234 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
natural phaeosphaeride A |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
antitumor activity |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
human tumor cell lines |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HEF cell line |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
acute toxicity |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
aspidosperma-type |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
monoterpenoid indole alkaloids |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
antiproliferative activity |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
tubulin inhibitor |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Bousigonia mekongensis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
ursolic acid |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
DOTA |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
triterpenoids |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cytotoxicity |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
diterpenoid alkaloids |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
human tumor cells |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
lipojesaconitine |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
delcosine |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
delpheline |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
kobusine |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
pseudokobusine |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
BRAF inhibitor |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Mentha aquatica var. Kenting Water Mint |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
essential oil |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
chemoprevention |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
two-stage skin carcinogenesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
melanoma |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
curcumin analog |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
apoptosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
oxidative stress |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
drug-drug interaction |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
tamoxifen |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
taxol |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cisplatin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Artemisia absinthium L. |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
antioxidants |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
total phenolic content |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
melanoma and breast cancer cell line |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HaCaT cells |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
inflammation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
breast cancer |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cell cycle |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
flavonoids |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
reactive oxygen species |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
tumor suppression |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
antiretroviral agents |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
anti-HIV |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
marine metabolites |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
natural products |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
drug development |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Ivalin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Carpesium divaricatum |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
hepatocellular carcinoma |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
mitochondria-mediated apoptosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
NF-κB |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Hernandia nymphaeifolia |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
butanolides |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
lignan glycosides |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
coumarins |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
antiangiogenic |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cancer |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
natural agents |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
chemistry |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
medicine |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cancer stem cell |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cervical cancer |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
pterostilbene |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
resveratrol |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
caffeic acid |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cancer multidrug resistance |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
P-glycoprotein |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
phenolic acid |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
oxypeucedanin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Angelica dahurica |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
antiproliferation |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
G2/M phase cell cycle arrest |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
p53 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SK-Hep-1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
hepatoma cells |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
allyl isothiocyanate |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
benzyl isothiocyanate |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
sulforaphane |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
phenethyl isothiocyanate |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
bladder cancer |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
quercetin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
oral squamous cell carcinoma cells |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
metastasis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cell cycle arrest |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
epithelial-to-mesenchymal transition |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
matrix metalloproteinase |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
transforming growth factor-β1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
β-lapachone |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nakagawa-Goto, Kyoko |
| Relator code |
oth |
| 9 (RLIN) |
1622670 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/2856">https://mdpi.com/books/pdfview/book/2856</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/69087">https://directory.doabooks.org/handle/20.500.12854/69087</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
